Which vaccine is contraindicated in children with a history of anaphylaxis to neomycin?

The MMR vaccine, which protects against measles, mumps, and rubella, is contraindicated for children who have a history of anaphylaxis to neomycin. This is significant because the MMR vaccine contains neomycin as a part of its formulation, and administering it to a child with such a history poses a risk of a severe allergic reaction.

Understanding this contraindication is important for ensuring the safety of pediatric patients when administering vaccinations. While the DTaP, polio, and varicella vaccines do not have neomycin as a component, the MMR’s inclusion of this antibiotic directly links it to the risk for those with neomycin allergies, making it the specific concern. Therefore, when assessing vaccination options for children with known allergies, such knowledge is crucial for healthcare providers.